AASraw
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- Oct 22, 2017
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Choosing the right PDE5 inhibitor can depend on a variety of factors, including the patient’s overall health, the presence of other conditions, their lifestyle, and their individual response to medication. Here is a general guide to choosing a PDE5 inhibitor for reference, but remember to always consult with a healthcare provider to make the best choice for individual needs.
Notes: This information about PDE5 inhibitors is provided for general informational purposes only and does not constitute medical advice. The choice of a PDE5 inhibitor should always be made in consultation with a healthcare provider who can take into account the individual’s overall health, other medications being taken, and the specific nature and severity of the erectile dysfunction. While these medications can be effective in treating erectile dysfunction, they also have potential side effects and risks, and they are not suitable for everyone. Certain health conditions and other medications may interact with PDE5 inhibitors, leading to potentially serious adverse effects. Always seek the advice of a healthcare provider for any questions you may have regarding a medical condition.
| Patient Condition | Recommended PDE5 Inhibitor | Reason |
| A desire for fast onset time | Avanafil | Fastest onset among the PDE5 inhibitors |
| Middle-aged and elderly with ED and chronic diseases (hypertension, hyperlipidemia) | Sildenafil | Average pharmacokinetic parameters, less stimulation to the body |
| Middle-aged and elderly with ED and vascular endothelial dysfunction (e.g.diabetes) | Tadalafil | Long duration of action, can improve vascular endothelial function and urinary tract symptoms over time |
| Middle-aged and elderly with ED, no vascular diseases | Vardenafil | Mild effect, quick onset, low bioavailability, few adverse reactions |
| Middle-aged and elderly with ED, vascular endothelial dysfunction, sildenafil ineffective | Avanafil | High blood concentration, a strong effect |
| Young and middle-aged with ED, no obvious organic etiology | Sildenafil | Effective for ED caused by psychological factors |
| Abnormal visual function and ED | Tadalafil | No visual abnormalities among adverse reactions |
| Postprandial medication preference | Avanafil, Vardenafil | Absorption rate not easily affected by food |
Notes: This information about PDE5 inhibitors is provided for general informational purposes only and does not constitute medical advice. The choice of a PDE5 inhibitor should always be made in consultation with a healthcare provider who can take into account the individual’s overall health, other medications being taken, and the specific nature and severity of the erectile dysfunction. While these medications can be effective in treating erectile dysfunction, they also have potential side effects and risks, and they are not suitable for everyone. Certain health conditions and other medications may interact with PDE5 inhibitors, leading to potentially serious adverse effects. Always seek the advice of a healthcare provider for any questions you may have regarding a medical condition.
