CatDaddy
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- Mar 12, 2017
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TUDCA (Tauroursodeoxycholic Acid) is known in the bodybuilding community for its amazing properties as a liver protection compound. What goes untold or even unknown is the additional benefits that can come from taking TUDCA.
Below is a link to an APA Article by Sheila Vang, Katie Longley and Walter C. Low Titled: "The Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver Diseases"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030606/
This article covers information on the positive affects TUDCA has on:
amyotrophic lateral sclerosis
Alzheimer's disease
Parkinson's disease
Huntington's disease
protecting against cell death in certain retinal disorders
retinitis
Obesity
stroke
acute myocardial infarction
spinal cord injury
GI disorders and IBS
If you don't feel like reading the whole article or clicking the link here is the Abstract:
"Tauroursodeoxycholic acid (TUDCA) is the taurine conjugate of ursodeoxycholic acid (UDCA), a US Food and Drug Administration–approved hydrophilic bile acid for the treatment of certain cholestatic liver diseases. There is a growing body of research on the mechanism(s) of TUDCA and its potential therapeutic effect on a wide variety of non-liver diseases. Both UDCA and TUDCA are potent inhibitors of apoptosis, in part by interfering with the upstream mitochondrial pathway of cell death, inhibiting oxygen-radical production, reducing endoplasmic reticulum (ER) stress, and stabilizing the unfolded protein response (UPR). Several studies have demonstrated that TUDCA serves as an anti-apoptotic agent for a number of neurodegenerative diseases, including amyotrophic lateral sclerosis, Alzheimer's disease, Parkinson's disease, and Huntington's disease. In addition, TUDCA plays an important role in protecting against cell death in certain retinal disorders, such as retinitis pigmentosa. It has been shown to reduce ER stress associated with elevated glucose levels in diabetes by inhibiting caspase activation, up-regulating the UPR, and inhibiting reactive oxygen species. Obesity, stroke, acute myocardial infarction, spinal cord injury, and a long list of acute and chronic non-liver diseases associated with apoptosis are all potential therapeutic targets for T/UDCA. A growing number of pre-clinical and clinical studies underscore the potential benefit of this simple, naturally occurring bile acid, which has been used in Chinese medicine for more than 3000 years."
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Below is a link to an APA Article by Sheila Vang, Katie Longley and Walter C. Low Titled: "The Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver Diseases"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030606/
This article covers information on the positive affects TUDCA has on:
amyotrophic lateral sclerosis
Alzheimer's disease
Parkinson's disease
Huntington's disease
protecting against cell death in certain retinal disorders
retinitis
Obesity
stroke
acute myocardial infarction
spinal cord injury
GI disorders and IBS
If you don't feel like reading the whole article or clicking the link here is the Abstract:
"Tauroursodeoxycholic acid (TUDCA) is the taurine conjugate of ursodeoxycholic acid (UDCA), a US Food and Drug Administration–approved hydrophilic bile acid for the treatment of certain cholestatic liver diseases. There is a growing body of research on the mechanism(s) of TUDCA and its potential therapeutic effect on a wide variety of non-liver diseases. Both UDCA and TUDCA are potent inhibitors of apoptosis, in part by interfering with the upstream mitochondrial pathway of cell death, inhibiting oxygen-radical production, reducing endoplasmic reticulum (ER) stress, and stabilizing the unfolded protein response (UPR). Several studies have demonstrated that TUDCA serves as an anti-apoptotic agent for a number of neurodegenerative diseases, including amyotrophic lateral sclerosis, Alzheimer's disease, Parkinson's disease, and Huntington's disease. In addition, TUDCA plays an important role in protecting against cell death in certain retinal disorders, such as retinitis pigmentosa. It has been shown to reduce ER stress associated with elevated glucose levels in diabetes by inhibiting caspase activation, up-regulating the UPR, and inhibiting reactive oxygen species. Obesity, stroke, acute myocardial infarction, spinal cord injury, and a long list of acute and chronic non-liver diseases associated with apoptosis are all potential therapeutic targets for T/UDCA. A growing number of pre-clinical and clinical studies underscore the potential benefit of this simple, naturally occurring bile acid, which has been used in Chinese medicine for more than 3000 years."
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